EsturgeonV1, Main, Exploration, bibRecord, 000445

Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost.

Identifieur interne : 000445 ( Main/Exploration ); précédent : 000444; suivant : 000446

Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost.

Auteurs : Yi Li [Royaume-Uni] ; Armin Sturm ; Phil Cunningham ; Nicolas R. Bury

Source :

BMC evolutionary biology [ 1471-2148 ] ; 2012.

RBID : pubmed:22862956

English descriptors

KwdEn :
- Animals, Evolution, Molecular, Fish Proteins (chemistry), Fish Proteins (genetics), Fishes (genetics), Phylogeny, Protein Structure, Tertiary, Receptors, Glucocorticoid (chemistry), Receptors, Glucocorticoid (genetics).
MESH :
- chemical , chemistry : Fish Proteins, Receptors, Glucocorticoid.
- chemical , genetics : Fish Proteins, Receptors, Glucocorticoid.
- genetics : Fishes.
- Animals, Evolution, Molecular, Phylogeny, Protein Structure, Tertiary.

Abstract

Duplicated glucocorticoid receptors (GR) are present in most teleost fish. The evolutionary advantage of retaining two GRs is unclear, as no subtype specific functional traits or physiological roles have been defined. To identify factors driving the retention of duplicate GRs in teleosts, the current study examined GRs in representatives of two basal ray-finned fish taxa that emerged either side of the teleost lineage whole genome duplication event (WGD) event, the acipenseriform, Acipenser ruthenus, (pre-WGD) and the osteoglossimorph, Pantodon buchholzi, (post-WGD).

DOI: 10.1186/1471-2148-12-137
PubMed: 22862956

Affiliations:

Royaume-Uni

Le document en format XML

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<author><name sortKey="Li, Yi" sort="Li, Yi" uniqKey="Li Y" first="Yi" last="Li">Yi Li</name>
<affiliation wicri:level="1"><nlm:affiliation>Nutritional Sciences Research Division, King's College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Nutritional Sciences Research Division, King's College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH</wicri:regionArea>
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<series><title level="j">BMC evolutionary biology</title>
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<front><div type="abstract" xml:lang="en">Duplicated glucocorticoid receptors (GR) are present in most teleost fish. The evolutionary advantage of retaining two GRs is unclear, as no subtype specific functional traits or physiological roles have been defined. To identify factors driving the retention of duplicate GRs in teleosts, the current study examined GRs in representatives of two basal ray-finned fish taxa that emerged either side of the teleost lineage whole genome duplication event (WGD) event, the acipenseriform, Acipenser ruthenus, (pre-WGD) and the osteoglossimorph, Pantodon buchholzi, (post-WGD).</div>
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Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost.

Evidence for a divergence in function between two glucocorticoid receptors from a basal teleost.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

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